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Emerald BioStructures announces discovery of small molecule modulators of PDE4

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12/27/09 ( MacDougall Biomedical Communications, Inc. ) Emerald BioStructures announced today a publication in the Dec. 27, 2009, advance online issue of Nature Biotechnology, detailing the application of structure-based drug design to engineer new allosteric small molecule modulators of the enzyme phosphodiesterase-4 (PDE4), with reduced side effects. According to the paper, the researchers established ...
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    Castor Bean Genome Published By Research Team Including Scientists From The Venter Institute

    08/24/10 A research team co-led by scientists from the J. Craig Venter Institute (JCVI) and the Institute for Genome Sciences (IGS), University of Maryland School of Medicine, published the sequence and analysis of the castor bean (Ricinus communis) genome in Nature Biotechnology. Agnes P. Chan, Ph.D., JCVI, and Jonathan Crabtree, Ph.D., IGS were co-lead authors on the paper describing the 4.5X coverage ...
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    Metabolism models may explain why Alzheimer's disease kills some neuron types first

    12/06/10 Bioengineers from the University of California, San Diego developed an explanation for why some types of neurons die sooner than others in the brains of people with Alzheimer's disease. These insights, published in the journal Nature Biotechnology on November 21, come from detailed models of brain energy metabolism developed in the Department of Bioengineering at the UC San Diego Jacobs School ...
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    New Method Developed For Delivering Drugs To The Brain - Alzheimer's Society Comment

    03/21/11 Scientists have developed a new way of administering drugs to the brain to treat Alzheimer's disease, according to a study published last Sunday in 'Nature Biotechnology'. Researchers at Oxford University injected exosomes - tiny particles naturally released by cells - into the blood of mice. They found that for the first time, using this 'natural' system they were able to transfer potential new ...
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